CMO supplement review, health benefit, for arthritis and osteoarthritis
Dosage and side effects, Cetyl myristoleate product
Does it benefit or cure arthritis symptoms? Does it relieve joint pain?
Use in dogs, pets, horses, cats, what is the right dose?
February 1 2017

CMO source
Cetyl myristoleate is a dietary supplement that contains a concentrated extract of the fatty acid cerasomal-cis-9-acetyl-myristoleate from natural bovine source. CMO is not found in vegetable oils or other common foods but is found in low amounts in animal connective tissue.

Benefit, how it can help you
This product is often used by those who wish to treat symptoms of arthritis or osteoarthritis. There are few human studies with this substance.

CMO may have a benefit for arthritis treatment, but most likely it will be more effective in combination with other supplements that are of help for joint aches and pains. This ingredient is found in a popular joint formula called Joint Power Rx, developed by a well-respected physician.

How is CMO available? What products are sold online or in health food stores? Where to buy
You can find a number of manufacturers that make CMO supplements in varying dosages. Some products for arthritis pain relief and joint health support also include this nutrient. One such popular product is Joint Power Rx with glucosamine, chondroitin, MSM, turmeric, boswellia, and cat’s claw. It is formulated by a medical doctor. Here is a high quality product available online.


CMO – Cetyl Myristoleate complex – 550 mg each capsule – Fatty acid complex with cetyl myristoleate at 20 percent

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Dosage: One to three capsules daily or as suggested by your doctor. If you buy Joint Power Rx in addition to the CMO, you could take, in the morning before breakfast, one capsule of the CMO in addition to 3 or 4 Joint Power Rx pills.

Arthritis and Osteoarthritis review
There are many herbal extracts and nutritional supplements, for instance Chondroitin and MSM, that can be of benefit, either alone, or in a joint formula, to help with symptom reduction.

Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence.
Arthritis Research Ther. 2006; Ameye LG. Nutrition and Health Department, Nestlé Research Center, Vers-chez-les-Blanc, Switzerland
The scientific and medical community remains skeptical regarding the efficacy of nutrition for osteoarthritis despite their broad acceptation by patients. this paper reviews human clinical trials evaluating the effects of nutritional compounds on osteoarthritis. We searched the Medline, Embase, and Biosis databases using the terms random, double-blind method, trial, study, placebo, and osteoarthritis. We selected all peer-reviewed articles reporting the results of randomised human clinical trials (RCTs) in osteoarthritis that investigated the effects of oral interventions based on natural molecules. Studies on glucosamine and chondroitin sulfate were excluded. Good evidence was found for avocado soybean unsaponifiables. Moderate evidence was found for methylsulfonylmethane and SKI306X, a cocktail of plant extracts. Limited evidence was found for the Chinese plant extract duhuo jisheng Wan, CMO cetyl myristoleate, lipids from green-lipped mussels, and plant extracts from Harpagophytum procumbens. Overall, scientific evidence exists for some specific nutritional interventions to provide symptom relief to osteoarthritic patients. It remains to be investigated whether nutritional compounds can have structure-modifying effects.

Rheumatoid arthritis
At this time we have not seen studies with CMO in regards to the natural treatment of rheumatoid arthritis.

Use in horses, cats, pets, dogs
We have seen little research to determine whether CMO is helpful in animals, but it is worth a try. Some owners report positive results. The dose is difficult to know but would be based on the weight of the animal.

Creams applied topically
CMO Cream is available in some stores and online to rub into sore joints and muscles. A few products contain additional substances such as MSM, PPG-2, vitamin E, and glycerin. Some people have noticed good results.

CMO cream, cetylated fatty acids
Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis.
J Rheumatol. 2004; Kraemer WJ, Ratamess NA, Maresh CM, Tiberio DP, Messinger BN, Rubin MR, Volek JS, Hesslink R Jr. Human Performance Laboratory, School of Medicine, University of Connecticut, Storrs, Connecticut, USA.
To examine the effect of a topical cream consisting of cetylated fatty acids on functional performance in patients diagnosed with osteoarthritis of one or both knees. Forty patients diagnosed with knee osteoarthritis were randomly assigned to one of 2 topical treatment groups: cetylated fatty acid (CFA) or placebo group. Use of a CFA topical cream is an effective treatment for improving knee range of motion, ability to ascend/descend stairs, ability to rise from sitting, walk and sit down, and unilateral balance.

Other products sold online
CMO along with several other fatty acids including cetyl myristate, cetyl palmitate, cetyl laurate, cetyl palmitoleate, and cetyl oleate.

CMO with the three digestive enzymes and selenium. Vestalcare Original CMO is a beef tallow extract combined WITH Amylase, Protease, and Lipase.

Cetyl Myristoleate 260mg
Cetyl Myristate 349mg, Other Cetyl Esters 47mg

We are not aware of it being sold in tablet form.

Suppliers and manufacturers
My name is Joel Lerner with EHP Products. We’re the family company of the discoverer of Cetyl Myristoleate, an effective joint support ingredient. We are the original marketer of CMO. Our President is Harry Diehl’s daughter, and we have a vested interest to uphold his legacy by employing the most stringent standards. EHP Products carries all forms of CMO. We also have our own line of CMO products including a 260mg (actual CMO amount) softgel, a 5% CMO cream, and a supporting product called Myrist-Aid. They are all available for private label. Our line of products are unique. What differentiates our softgels is that we make them out of the only low melting point mixed cetyl esters in the world. All other CMO products contain high melting point mixed cetyl esters. This means their products must be sprayed onto a carrying powder or diluted with an unsaturated oil. Both processes cut the CMO strength way down. We do not have to dilute our low melting point cetyl esters to get the product into a softgel. This means our 650 mg mixed cetyl esters softgel has 260 mg of molecular CMO. Most other products have 500 or 550 mg of cetyl esters powder, but only 110 mg of molecular CMO or even less. However, their label claims may state something like CMO Complex 500mg. Unfortunately, some companies choose not to label their products with the amount of molecular CMO, which makes deciphering the actual ingredient amount difficult. As the discoverer’s family company, we hold ourselves to a higher standard. As previously mentioned, we also have a topical 5% CMO cream and a product called Myrist-Aid, both of which enhance the effectiveness of our straight CMO softgel product called Myristin. Myrist-Aid includes Glucosamine Sulfate, MSM, Lipase, Lecithin, Vitamin C, Manganese Citrate, Curcumin and Bromelain. These 3 products can be sold individually to your customers or as a Joint Support Wellness Kit as they work synergistically. To reiterate, all of our products are available for private label. Regarding our CMO cream, it would be very hard (impossible I think) for anyone to get 5% CMO in a cream if they don’t use our 40% oil. That’s because the amount of the esters in some carrier oil required for 5% CMO would make the product runny, not creamy. In other words, we use 7.5 grams of our 40% oil per 60 grams of cream. If you have a 20% CMO oil in olive oil, then you need to use 15 grams of that product per 60 grams of cream, and I don’t know how you could keep that from being runny. Our 5% CMO employs the use of Lipoceuticals. Liposeuticals have signaled a revolutionary method of formulating topical products with the benefits of efficacy, safety, and patient acceptability. Lipoceuticals incorporate the use of liposomes, which are microscopic vesicles composed of membrane-like lipid bi-layers separated by an aqueous layer with an aqueous center. Lipoceuticals are liposomes in a multiphase system that contain an active ingredient in each phase. The advantage is that liposomes allow the incorporation of a variety of lipophilic and hydrophilic ingredients to enhance delivery and improve product performance. What this means to EHP’s customers is that permeation of the area to which Myristin Cream is applied is greater with liposomes, and systemic absorption is reduced compared to non-liposomal topical products. Please note our approach to wellness with CMO is unique. Most companies combine the supporting ingredients with CMO in the same product, and there’s nothing wrong with that. However, that’s not the way to achieve wellness in the fastest manner. Also our softgels have the most CMO available anywhere at 260 mg, and our cream has the highest CMO amount of any cream. Please contact me if you’d like to discuss adding it to your present formula and/or adding it as a stand alone product to your line. Yours in good health, Joel Lerner of EHP Products